Inactivation of gonococci by procaine penicillin in vivo. A pilot study.
نویسندگان
چکیده
A pilot study was carried out of 25 male volunteers with gonococcal urethritis. After intramuscular administration of 3 megaunits procaine penicillin and 1 g oral probenecid the urethral culture results for Neisseria gonorrhoeae remained positive up to five hours and thereafter became negative. These results may be useful in providing guidelines for advice on the duration of sexual abstinence following treatment. It is suggested that similar studies should be carried out in women.
منابع مشابه
High dosage procaine penicillin combined with ampicillin in the treatment of gonorrhoea after failure with standard procaine penicillin dosage.
This is a preliminary report suggesting a method of management of cases of gonorrhoea in which there has been failure of treatment with standard doses of penicillin. Over the past 10 years there has been a steady increase in the number of strains of gonococci isolated which show an increased resistance to the action of penicillin (Curtis and Wilkinson, 1958). The Medical Research Council (1961)...
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عنوان ژورنال:
- The British journal of venereal diseases
دوره 54 6 شماره
صفحات -
تاریخ انتشار 1978